Harlequin Great Dane puppies for sale attract dog lovers with their eye-catching black-and-white coat patterns and affectionate, gentle personalities. These majestic giants—often referred to as Harlequin Danes—combine elegance, impressive size, and a loyal temperament. As a result, they’re a popular choice for families and individuals who have the space and time to care for a large breed dog. In this ultimate guide, you’ll discover everything you need to know about Harlequin Great Dane puppies for sale, including their distinctive traits, care needs, health considerations, how to choose a reputable breeder, and tips for preparing your home for a giant breed puppy.

What Makes Harlequin Great Dane Puppies Unique?
Understanding the Harlequin Coat Pattern
Harlequin Great Danes feature a white base coat covered with irregular black patches, a hallmark defined by the American Kennel Club (AKC). According to the AKC, an ideal Harlequin should have a pure white neck and balanced black patches—neither oversized like a blanket nor tiny like stippling.
Some Harlequins display mismarked patterns like gray, blue, or fawn patches. While these markings don’t meet AKC standards, they still captivate pet owners with their charm. Merle Great Dane puppies are genetically related to Harlequins via the merle gene. However, the Harlequin coat stands out due to its bold black-and-white contrast.
Young Harlequin puppies may resemble Dalmatians due to their spotted appearance, but as they grow, the spots develop into larger, more dramatic patches. For example, their towering height—often reaching 32 inches at the shoulder—paired with this striking coat makes Harlequin Danes truly unforgettable.
History and Origins of the Harlequin Great Dane
The Great Dane breed, including the Harlequin variety, originated in Germany nearly 400 years ago. Breeders combined Irish Wolfhounds and English Mastiffs to produce powerful dogs capable of hunting wild boar. Over time, the German nobility refined these dogs into noble companions and reliable guardians.
The harlequin coat pattern—closely linked to the merle gene—emerged as a distinctive and desirable trait. However, breeding two Harlequins or merles can result in double merle puppies, which face significant health risks, including deafness, blindness, or stillbirth.

Why Choose Harlequin Great Dane Puppies for Sale?
If you’re considering bringing a giant breed into your home, Harlequin Great Dane puppies for sale stand out for their striking appearance, loyal temperament, and gentle personality. These beautiful dogs combine the size and strength of a Great Dane with the unique black-and-white harlequin coat, making them one of the most eye-catching and affectionate breeds available today.
Temperament and Personality of Harlequin Great Danes
Harlequin Great Danes offer the same lovable traits that define the breed: gentle, loyal, and incredibly friendly. Despite their towering height, these gentle giants often behave like oversized lap dogs, craving human attention and affection. They bond quickly with family members, including children, and usually welcome strangers with a calm, friendly demeanor.
Moreover, Harlequin Great Dane puppies are eager to please, which makes them easy to train. Their protective instincts also make them excellent watchdogs. However, early socialization is crucial to ensure they grow into well-mannered, confident adults.
Are Harlequin Great Danes Good Family Pets?
Yes—Harlequin Great Dane puppies make fantastic family companions, especially in homes with enough space. They adapt well to indoor living, as long as they get daily outdoor time and interaction. When properly socialized, they get along well with other pets and children.
However, due to their size and playful energy, it’s best to supervise them around small kids to prevent accidental bumps or knocks. Their affectionate and playful nature makes them a joyful addition to any household.
Health Considerations for Harlequin Great Dane Puppies
Common Health Issues
Like other giant breeds, Harlequin Great Danes face several health challenges due to their size and genetic background. Responsible ownership and breeder selection can help reduce risks. Common concerns include:
- Dilated Cardiomyopathy (DCM): A heart condition often seen in Great Danes. Regular vet checkups are essential for early detection.
- Hip Dysplasia: This joint disorder is common in large dogs. Ethical breeders screen for it before breeding.
- Bloat (Gastric Dilatation Volvulus): A dangerous, life-threatening condition where the stomach twists. Learn to recognize symptoms such as restlessness, drooling, or a swollen abdomen.
- Wobbler Syndrome: A spinal disease that causes instability in the neck, leading to coordination issues. In severe cases, surgery may be necessary.
- Merle Gene Risks: Harlequin coloring results from merle genetics. Breeding two merle carriers can result in puppies with hearing or vision loss. Ethical breeders avoid such pairings.
With attentive care, a Harlequin Great Dane’s lifespan typically ranges from 7 to 10 years.
Essential Harlequin Great Dane Puppy Care Tips
Diet and Nutrition
Feed your puppy a high-quality, large-breed puppy food formulated with the correct calcium and phosphorus ratio to support joint health and controlled growth. Avoid overfeeding, which can cause skeletal problems. Generally, the transition to adult food occurs around 12 to 15 months of age. Always consult your veterinarian for personalized feeding advice.
Grooming
Harlequins have short, smooth coats that require minimal grooming. A weekly brushing helps control shedding and keeps their coat shiny. Bathing should be occasional unless they get especially dirty.
Exercise Needs
Great Dane puppies need daily walks and mental stimulation but should avoid intense exercise during early development. Short, gentle play sessions are ideal for protecting growing joints.
Where to Find Harlequin Great Dane Puppies for Sale
If you’re searching for a loyal, affectionate, and majestic companion, Harlequin Great Dane puppies for sale offer the perfect combination of striking beauty and gentle temperament. Known for their white coats with bold black patches, these puppies grow into giant yet loving family members. But finding the right Harlequin Great Dane starts with knowing what to look for—and who to trust.

How to Choose the Right Harlequin Great Dane Puppy
When selecting a Harlequin Great Dane puppy, prioritize health, temperament, and breeder ethics over appearance alone. Choosing a reputable breeder ensures your puppy grows into a healthy, well-socialized dog. Look for these key factors:
Health Testing
Top Harlequin Great Dane breeders conduct thorough health screenings for common issues like:
- Hip Dysplasia
- Dilated Cardiomyopathy (DCM)
- Merle Gene Complications
Responsible breeders provide health certificates for the puppy’s parents.
Champion Bloodlines
Puppies from champion or European bloodlines often show stronger conformation and predictable temperament. For example, at [adoptgreatdane.com], we offer AKC Harlequin Great Dane puppies bred from award-winning lines.
Transparency and Trust
Trustworthy breeders are open about their breeding practices. They allow visits or video calls to meet the puppy’s parents and observe living conditions. Ask questions about:
- Socialization routines
- Parent temperaments
- Vaccination records
Socialization
The best breeders raise puppies in family homes, not kennels, exposing them to children, pets, and everyday sounds. Early socialization builds confident, calm adult dogs.
Avoid breeders who prioritize coat color over health or structure—this often leads to costly long-term issues.
Best Place to Find Harlequin Great Dane Puppies for Sale
The best place to find healthy, well-socialized Harlequin Great Dane puppies for sale is through a breeder who prioritizes health, temperament, and ethical practices. At [AdoptGreatDane.com], we offer everything you need to confidently bring home a Harlequin Great Dane puppy.
Why Choose AdoptGreatDane.com?
- Health-Tested Puppies: All our Harlequin Great Dane puppies come from parents screened for common breed-related issues such as hip dysplasia, DCM, and merle gene risks.
- Champion Bloodlines: Our dogs are bred from AKC-registered champion lines, ensuring superior conformation and temperament.
- Transparent Process: We welcome video calls or in-person visits so you can meet the puppy’s parents and see how your future companion is raised.
- Early Socialization: Our puppies grow up in a home environment with kids, pets, and everyday sounds, ensuring balanced, family-ready dogs.
- Nationwide Delivery: No matter where you live in the U.S., we offer safe and reliable transportation options to bring your puppy home.
Instead of taking a chance on platforms or unknown breeders, work directly with us—a trusted Great Dane breeder with a proven reputation for quality, care, and long-term support.
Explore our available Harlequin Great Dane puppies now at AdoptGreatDane.com and reserve your perfect gentle giant today.
What Is the Cost of a Harlequin Great Dane Puppy?
Prices for Harlequin Great Dane puppies vary depending on the breeder’s reputation, lineage, and geographic region. Here’s a breakdown of what to expect:
Expense | Estimated Cost |
---|---|
Puppy Purchase Price | $600–$2,000+ |
Large Breed Puppy Food (Monthly) | $50–$100 |
Annual Veterinary Care | $500–$1,000 |
Supplies (Crate, Toys, Bed) | $200–$500 (one-time) |
Training Classes | $100–$300 |
Grooming Tools or Services | $50–$100/year |
Harlequin Great Danes from European or champion lines typically command higher prices. In contrast, rescue adoption ranges from $100 to $500 and offers a more budget-friendly alternative for experienced owners.
Harlequin Great Dane Puppies for Adoption
Choosing Harlequin Great Dane puppies for adoption offers a second chance to a loving companion. While puppies remain rare in rescue centers, some younger Harlequins become available when previous homes struggle with their size or care needs. Adoption not only saves lives—it also feels deeply rewarding and often reduces upfront costs. Consider these adoption options:
- Great Dane Rescues: Many specialize in rehoming purebred Danes, including Harlequins, with adoption fees typically between $100 and $500.
- Local Shelters: Nearby shelters occasionally offer Harlequin Great Dane puppies for adoption or rehome young adults in need.
- AKC Rescue Network: This nationwide network connects families with reputable Great Dane rescues across the U.S.
To adopt, complete an application, schedule a home visit, and participate in an interview. In most cases, you must also provide references and show that you’re ready to care for a large breed puppy.

Preparing Your Home for a Harlequin Great Dane Puppy
Getting your home ready for a Harlequin Great Dane puppy is essential for their safety, comfort, and successful adjustment. These gentle giants grow quickly and require both space and durable supplies. Follow these preparation tips:
- Puppy-Proofing: Remove household hazards such as electrical cords, toxic plants, and small choking hazards. Always secure trash cans to prevent scavenging.
- Essential Supplies: Choose a large crate (42–48 inches), chew-resistant toys, and a supportive bed made for large breeds. Use raised bowls to support healthy digestion.
- Space to Grow: Offer plenty of room indoors and, if possible, a fenced yard for safe playtime.
- Comfort Zone: Create a quiet, low-traffic area where your puppy can rest during growth spurts.
Additionally, ask your breeder or rescue for product suggestions that suit Great Danes’ unique needs.
Breeder Red Flags and Scams to Avoid
When looking for Harlequin Great Dane puppies for sale, stay alert for unethical breeders and scams. Protect yourself by avoiding these common red flags:
- Lack of Health Testing: Ethical breeders provide proof of testing for hip dysplasia and dilated cardiomyopathy (DCM).
- No Parent Information: Avoid breeders unwilling to share photos, names, or details of the puppy’s parents.
- Suspiciously Low Prices: Offers under $600 often signal puppy mills or online scams.
- Poor Communication: Reputable breeders answer questions openly and avoid pressuring buyers.
- No Return Policy: A reliable breeder offers a health guarantee and agrees to take the puppy back if needed.
To verify breeder credibility, check AKC Marketplace reviews, ask for references, or contact local kennel clubs. As a rule of thumb, avoid sellers operating exclusively online without a traceable business.
Harlequin Great Dane Puppy Growth and Development
Monitoring your Harlequin Great Dane puppy’s growth helps you meet their evolving needs at each stage. These gentle giants develop quickly and need special care during their first two years. Here’s what to expect:
- 0–3 Months: Puppies grow rapidly. Feed them 3–4 times daily with large-breed puppy food. Focus on socialization and start basic training.
- 3–6 Months: Growth accelerates. Their joints remain vulnerable, so avoid high-impact play. Begin formal obedience training with commands like “sit,” “stay,” and “come.”
- 6–12 Months: Most puppies reach 80–90% of their adult size (100–200 pounds). Transition to adult food around 12 months. Strengthen socialization through structured activities.
- 1–2 Years: Full physical maturity occurs. Males may reach up to 32 inches at the shoulder, with females slightly smaller. Maintain regular exercise and monitor for breed-specific health concerns.
Additionally, schedule regular veterinary checkups to track their growth and catch early signs of any health issues.
Comparing Harlequin Great Danes to Other Coat Colors
Harlequin Great Danes stand out with their striking coat pattern, making them a favorite among enthusiasts. However, it’s essential to compare them with other Great Dane coat colors to make an informed decision. Each coat comes with its own characteristics, health considerations, and popularity trends.
Coat Color | Description | Health Risks | Popularity |
---|---|---|---|
Harlequin | White base with irregular black patches | Merle gene risks (deafness, blindness) | High, due to unique appearance |
Fawn | Light tan with black mask | Fewer genetic risks | Very popular |
Brindle | Tiger-striped pattern | Fewer genetic risks | Moderately popular |
Mantle | Black and white, “blanket” pattern | Minimal genetic risks | Increasing in popularity |
Blue | Solid steel-blue color | Minimal genetic risks | Popular for sleek appearance |
Many compare Harlequin vs. Mantle Great Danes because both feature bold black-and-white coats. However, Harlequins carry the merle gene, which increases the risk of hearing or vision issues. In contrast, Mantles do not carry these risks. Despite this, Harlequins remain highly sought after for their one-of-a-kind appearance.
Harlequin Great Dane Puppy Training Guide
Training a Harlequin Great Dane puppy from an early age helps manage their large size and ensures good behavior. These dogs are highly intelligent and respond well to consistent, positive reinforcement. Use these training strategies:
- Basic Commands: Start with simple cues such as “sit,” “stay,” “come,” and “leave it.” Reward success with treats and praise.
- Leash Training: Choose a sturdy leash. Practice loose-leash walking to prevent pulling, which can be a challenge as they grow.
- Socialization: Introduce your puppy to new people, pets, and environments between 3 and 12 weeks of age to build confidence.
- Crate Training: Use an appropriately sized crate (42–48 inches) for house training and as a secure, quiet space.
Additionally, join local dog training classes for professional guidance. Although Harlequins are intelligent, they may show a stubborn streak—so stay patient and consistent.
What Families Say About Harlequin Great Danes
Hearing from real families offers insight into life with a Harlequin Great Dane. These personal stories highlight the breed’s affectionate nature, training needs, and everyday experiences:
- Sarah, Colorado: “Our Harlequin, Luna, loves cuddling with the kids. We worked with a reputable breeder to ensure her health.”
- Mark, UK: “Rescuing Max changed our lives. After a bloat scare, we learned the importance of managing feeding times.”
- Emily, Missouri: “Our European Harlequin has flawless markings. Crate training went well, but we definitely needed the biggest one available!”
These testimonials reveal the joys and challenges of owning a Harlequin Great Dane—from their affectionate personalities to their space and care requirements.

Frequently Asked Questions About Harlequin Great Dane Puppies for Sale
Are Harlequin Great Danes Good with Kids?
Harlequin Great Dane puppies interact well with children when socialized early. Their calm and gentle temperament suits families. However, always supervise playtime due to their large size to prevent accidental knocks.
How Much Exercise Do Harlequin Great Dane Puppies Need?
These puppies need moderate activity. Include short daily walks and structured playtime to protect their developing joints. As they grow, adult Harlequin Great Danes thrive on 30 to 60 minutes of exercise each day to stay healthy and happy.
What Should I Ask a Breeder?
Ask breeders about health screenings, the temperament of the parents, socialization practices, and return policies. Additionally, request parent health certifications and ask to meet the puppies in person if possible. This ensures transparency and helps build trust with the breeder.
How Do I Find Harlequin Great Dane Puppies Near Me?
Start by searching on trusted platforms like the AKC Marketplace or Pets4Homes. You can also reach out to your local kennel clubs or visit breeder facilities to meet available Harlequin Great Dane puppies. Always prioritize ethical breeders who focus on health, socialization, and breed standards.
Can Harlequin Great Danes Live in Apartments?
Yes, they can adapt to apartment living if given adequate daily exercise and mental stimulation. Nevertheless, a home with a fenced yard offers more freedom of movement and better suits their size. No matter the space, these dogs need regular activity and companionship.
How Do I Prevent Bloat in Harlequin Great Dane Puppies?
To reduce the risk of bloat—a serious condition in large breeds—feed your puppy small, frequent meals. Choose a high-quality large-breed puppy formula and avoid intense exercise right after feeding. Furthermore, monitor for early symptoms like pacing or abdominal discomfort, and consult your vet promptly if you notice anything unusual.
Are Harlequin Great Danes Prone to Shedding?
Yes, Harlequin Great Danes shed moderately throughout the year. Their short coat is easy to manage with weekly brushing, which helps reduce shedding and keeps their skin healthy. Consider using a soft-bristle brush or grooming glove for the best results.
Conclusion: Bring Home a Loyal, Loving Harlequin Great Dane
Harlequin Great Dane puppies for sale offer more than just a striking appearance—they bring unmatched loyalty, gentle affection, and playful energy to the right home. With proper care, early training, and responsible breeding, these gentle giants grow into devoted family companions.
By choosing a reputable Harlequin Great Dane breeder, staying ahead of common health concerns, and following expert puppy care tips, you’re setting the foundation for a rewarding lifelong bond.
Ready to welcome your Harlequin Great Dane puppy? Visit AdoptGreatDane.com to explore our available puppies and reserve your future best friend today.